Drugs, Pharma, Natural Products & Cosmetics
DETERMINATION OF (S)-CARVONE BY HPLC+GC-MS IN ESSENTIAL OIL OF CARUM CARVI (CARAWAY) SEEDS
Courtesy of Rosa M. Martínez and Marta Herraiz. Instituto de Fermentaciones Industriales, CSIC, Madrid, Spain
A method is developed based on the TOTAD interface in the on-line coupling between RPLC+GC-MS for the determination of chiral volatile compounds.
In the research of alternative natural sources for chiral components from essential oils, such as carvone, the multidimensional technique GCxGC is often employed due to the overlapping of the chiral analyte with other matrix components. However, HPLC+GC can be a good alternative for their analysis, even working in reverse phase, allowing the acquisition of chromatograms with user-friendly software for the identification of these compounds.